Vai al contenuto
MICMedical Intelligence Core
Motore documentale attivo
🇬🇧 UK English Ricerca anonima
Medical Intelligence Core

Centri e Trial

Modulo Medical Intelligence Core.

Centri e trial per nazione

Catalogo server-side delle sedi dichiarate negli studi sul carcinoma mammario presenti in ClinicalTrials.gov. La presenza in un trial non equivale a una certificazione generale del centro.

6000 sedi globali indicizzate · 2462 trial · 31 nazioni aggiornate · ultimo aggiornamento 2026-09-29 10:04:21 UTC

Fondazione IRCCS Istituto Nazionale dei Tumori

Milan, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Fondazione IRCCS Istituto Nazionale dei Tumori

Milan, Italy

PHASE1, PHASE2 · RECRUITING · NCT06330064

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

Fondazione Del Piemonte Per L'Oncologia Irccs Candiolo

Candiolo, Italy

PHASE1, PHASE2 · RECRUITING · NCT06330064

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

Azienda Socio Sanitaria Territoriale Niguarda (Grande Ospedale Metropolitano Niguarda)

Milan, Italy

PHASE1, PHASE2 · RECRUITING · NCT06330064

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

Istituto Nazionale Tumori Fondazione G. Pascale

Naples, Italy

PHASE1, PHASE2 · RECRUITING · NCT06330064

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Rome, Italy

PHASE1, PHASE2 · RECRUITING · NCT06330064

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

Istituto Clinico Humanitas

Rozzano, Italy

PHASE1, PHASE2 · RECRUITING · NCT06330064

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

Azienda Ospedaliero Universitaria di Bologna Policlinico di Sant'Orsola IRCCS (Istituto Di Ricerca E Di Cura A Carattere Scientifico)

Bologna, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Ospedale Policlinico San Martino IRCCS (Istituto Di Ricerca E Di Cura A Carattere Scientifico)

Genova, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Azienda Ospedaliero-Universitaria Policlinico di Modena

Modena, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Azienda Ospedaliera Universitaria Federico II Di Napoli

Naples, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Istituto Nazionale Tumori Fondazione Pascale IRCCS (Istituto Di Ricerca E Di Cura A Carattere Scientifico)

Naples, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Azienda Ospedaliero Universitaria Maggiore della Carità di Novara

Novara, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Istituto Oncologico Veneto

Padova, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Istituti Clinici Scientifici Maugeri Spa Società Benefit IRCCS (Istituto Di Ricerca E Di Cura A Carattere Scientifico)

Pavia, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Azienda Ospedaliero Universitaria Pisana

Pisa, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Fondazione Policlinico Universitario Agostino Gemelli IRCCS (Istituto Di Ricerca E Di Cura A Carattere Scientifico)

Rome, Italy

PHASE3 · RECRUITING · NCT05232916

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Istituto Europeo di Oncologia

Milan, Italy

PHASE1 · RECRUITING · NCT06400472

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

Istituto Europeo di Oncologia

Milan, Italy

PHASE3 · RECRUITING · NCT06982521

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

Istituto Europeo di Oncologia

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT03820830

Palbociclib for HR Positive / HER2-negative Isolated Locoregional Recurrence of Breast Cancer

Istituto Europeo di Oncologia

Milan, Italy

PHASE2 · RECRUITING · NCT07102381

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

Istituto Europeo di Oncologia

Milan, Italy

PHASE1 · RECRUITING · NCT07222267

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

Istituto Europeo di Oncologia

Milan, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

Istituto Europeo di Oncologia

Milan, Italy

PHASE1, PHASE2 · RECRUITING · NCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Istituto Europeo di Oncologia

Milan, Italy

PHASE2 · RECRUITING · NCT05503797

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

Istituto Europeo di Oncologia

Milan, Italy

PHASE1, PHASE2 · RECRUITING · NCT05768139

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Istituto Europeo di Oncologia

Milan, Italy

PHASE3 · RECRUITING · NCT05696626

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Istituto Europeo di Oncologia

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT02513394

PALbociclib CoLlaborative Adjuvant Study

Istituto Europeo di Oncologia

Milan, Italy

NA · RECRUITING · NCT07579117

Endoscopic Video-Assisted Nipple-Sparing Mastectomy

Istituto Europeo di Oncologia

Milan, Italy

· RECRUITING · NCT07583485

GIM27-THERapy: a Study to Describe the Effectiveness of Tucatinib in Combination With Capecitabine and Trastuzumab in the Treatment of Metastatic HER-2 Positive Breast Cancer Patients in Real World Setting

Istituto Europeo di Oncologia

Milan, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT06840483

Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

Istituto Europeo di Oncologia

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05382299

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Istituto Europeo di Oncologia

Milan, Italy

NA · RECRUITING · NCT06446882

Diagnostic HER2DX-guided Treatment for Patients wIth Early-stage HER2-positive Breast Cancer

Istituto Europeo di Oncologia

Milan, Italy

PHASE3 · RECRUITING · NCT07492641

BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

Ospedale degli Infermi - S.O.C.Oncologia

Biella, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

Ospedale di Bolzano - Oncologia Medica

Bolzano, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

Ospedale Ramazzini di Carpi

Carpi, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

IRCCS AOU San Martino-IST

Genova, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

ULSS 21 Legnago

Legnago, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

UOC Oncologia Medica - AOU Parma

Parma, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

Fondazione Salvatore Maugeri

Pavia, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

IRCCS Az Ospedaliera S.Maria Nuova

Reggio Emilia, Italy

NA · RECRUITING · NCT02102165

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

Istituto Oncologico Veneto IRCCS

Padova, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Istituto Oncologico Veneto IRCCS

Padova, Italy

NA · RECRUITING · NCT07140172

Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery

Policlinico Universitario "Agostino Gemelli

Rome, Italy

NA · RECRUITING · NCT07140172

Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery

Research Site

Naples, Italy

PHASE3 · RECRUITING · NCT07647328

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

Research Site

Naples, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Naples, Italy

PHASE3 · RECRUITING · NCT07205822

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

Research Site

Naples, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04214288

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Naples, Italy

PHASE3 · RECRUITING · NCT06952803

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Research Site

Naples, Italy

PHASE3 · RECRUITING · NCT06103864

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Research Site

Naples, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Naples, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT04644068

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04739761

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04784715

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04964934

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT02032823

Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06112379

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Research Site

Naples, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT03330847

To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05629585

A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04421963

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05374512

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04305496

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04494425

Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer

Research Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04711252

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06112379

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Research Site

Roma, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT03330847

To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05629585

A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04421963

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05374512

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04305496

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04711252

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

Research Site

Roma, Italy

PHASE3 · RECRUITING · NCT06103864

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04964934

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Research Site

Roma, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT04644068

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Research Site

Roma, Italy

PHASE3 · RECRUITING · NCT06952803

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Research Site

Roma, Italy

PHASE1, PHASE2 · RECRUITING · NCT05123482

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

Research Site

Roma, Italy

PHASE3 · RECRUITING · NCT07205822

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

Research Site

Roma, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04214288

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Roma, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Roma, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Florence, Italy

PHASE3 · RECRUITING · NCT07205822

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

Research Site

Florence, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Florence, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Florence, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Research Site

Florence, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Bologna, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Bologna, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04214288

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Research Site

Bologna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Bologna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Research Site

Bologna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Bologna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Padova, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Padova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Padova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Research Site

Padova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Padova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04739761

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Research Site

Padova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Misterbianco, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Research Site

Misterbianco, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Milan, Italy

PHASE3 · RECRUITING · NCT07647328

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

Research Site

Milan, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Milan, Italy

PHASE3 · RECRUITING · NCT07205822

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

Research Site

Milan, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04214288

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Milan, Italy

PHASE3 · RECRUITING · NCT06952803

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Research Site

Milan, Italy

PHASE3 · RECRUITING · NCT06103864

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Research Site

Milan, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT04644068

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Research Site

Milan, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Milan, Italy

PHASE1, PHASE2 · RECRUITING · NCT05123482

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04739761

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04784715

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04964934

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT02032823

Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06112379

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Research Site

Milan, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT03330847

To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05629585

A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04421963

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05374512

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04305496

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04494425

Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer

Research Site

Milan, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04711252

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

Research Site

Rozzano, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Rozzano, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Rozzano, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Rozzano, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Meldola, Italy

PHASE3 · RECRUITING · NCT07205822

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

Research Site

Meldola, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04214288

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Research Site

Meldola, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Meldola, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Monza, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04214288

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Research Site

Monza, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Bergamo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04305496

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Research Site

Bergamo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04711252

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

Research Site

Bergamo, Italy

PHASE3 · RECRUITING · NCT06103864

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Research Site

Bergamo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04964934

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

Research Site

Bergamo, Italy

PHASE3 · RECRUITING · NCT06952803

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Research Site

Bergamo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT00099437

Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.

Research Site

Bergamo, Italy

PHASE3 · RECRUITING · NCT07647328

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

Research Site

Bergamo, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Bergamo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04739761

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Research Site

Bergamo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Genoa, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Novara, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Torino, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Research Site

Trento, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05952557

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore

Roma, Italy

PHASE1, PHASE2 · RECRUITING · NCT04895709

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore

Roma, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Istituto Nazionale Tumori IRCCS Fondazione Pascale

Naples, Campania, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola

Bologna, Emilia-Romagna, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Cro-Irccs

Aviano, Friuli Venezia Giulia, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Ospedale San Martino

Genoa, Liguria, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Ospedale "Felice Lotti" Di Pontedera

Pontedera, Pisa, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Nuovo Ospedale di Prato-S.Stefano

Prato, Tuscany, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Istituto Europeo di Oncologia IRCCS

Milan, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Azienda Ospedaliera Universitaria Federico II

Naples, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Azienda Ospedaliero Universitaria Maggiore della Carità

Novara, Italy

PHASE2, PHASE3 · RECRUITING · NCT06926868

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Research Site

Prato, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Prato, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04862663

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Research Site

Prato, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04739761

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Research Site

Catania, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Catania, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04739761

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Research Site

Ancona, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04739761

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Research Site

Candiolo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05104866

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

Research Site

Candiolo, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Livorno, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Research Site

Negrar, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05113251

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

Clinical Trial Site

Avellino, Campania, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Bologna, Emilia-Romagna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Meldola, Emilia-Romagna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Modena, Emilia-Romagna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Reggio Emilia, Emilia-Romagna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Udine, Friuli Venezia Giulia, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Rome, Lazio, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Milan, Lombardy, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Rozzano, Lombardy, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Piacenza, Piacenza, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Alessandria, Piedmont, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Aviano, Pordenone, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Ancona, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Genova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Naples, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Padova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Clinical Trial Site

Pavia, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06016738

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

IOV - Istituto Oncologico Veneto - IRCCS

Padova, Veneto, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06065748

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

IOV - Istituto Oncologico Veneto - IRCCS

Padova, Veneto, Italy

PHASE2, PHASE3 · ACTIVE_NOT_RECRUITING · NCT04191499

A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer

IOV - Istituto Oncologico Veneto - IRCCS

Padova, Veneto, Italy

PHASE2, PHASE3 · RECRUITING · NCT07413939

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

IOV - Istituto Oncologico Veneto - IRCCS

Padova, Veneto, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT02568267

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

IOV - Istituto Oncologico Veneto - IRCCS

Padova, Veneto, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia

Candiolo, Torino, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT05548127

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)

Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia

Candiolo, Torino, Italy

PHASE1, PHASE2 · RECRUITING · NCT04895709

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

Azienda ULSS 8 Berica

Vicenza, Veneto, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Humanitas

Rozzano, Milano, Italy

PHASE1, PHASE2 · RECRUITING · NCT04895709

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1

Milan, Italy

PHASE1, PHASE2 · RECRUITING · NCT04895709

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

Istituto Nazionale Tumori IRCCS Fondazione Pascale

Naples, Italy

PHASE1, PHASE2 · RECRUITING · NCT04895709

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

ospedale le scotte-U.O.C. Immunoterapia Oncologica

Siena, Italy

PHASE1, PHASE2 · RECRUITING · NCT04895709

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola

Meldola, Emilia-Romagna, Italy

PHASE2 · RECRUITING · NCT07405801

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola

Meldola, Emilia-Romagna, Italy

PHASE3 · RECRUITING · NCT06790693

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola

Meldola, Emilia-Romagna, Italy

PHASE2, PHASE3 · RECRUITING · NCT07413939

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola

Meldola, Emilia-Romagna, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Humanitas Centro Catanese Di Oncologia

Misterbianco (CT), Sicily, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06065748

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Humanitas Centro Catanese Di Oncologia

Misterbianco (CT), Sicily, Italy

PHASE3 · RECRUITING · NCT06790693

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

Humanitas Centro Catanese Di Oncologia

Misterbianco (CT), Sicily, Italy

PHASE2, PHASE3 · RECRUITING · NCT07413939

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

Humanitas Centro Catanese Di Oncologia

Misterbianco (CT), Sicily, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Ospedale Civile - Livorno

Livorno, Tuscany, Italy

PHASE3 · RECRUITING · NCT06790693

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

Ospedale Civile - Livorno

Livorno, Tuscany, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04873362

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

Ospedale Civile - Livorno

Livorno, Tuscany, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

IRCCS Istituto Regina Elena (IFO)

Rome, Lazio, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Az. Osp. Spedali Civili

Brescia, Lombardy, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Istituto Europeo Di Oncologia

Milan, Lombardy, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Asst Di Monza

Monza, Lombardy, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Fondazione del Piemonte per l?Oncologia (IRCCS)

Candiolo, Trentino-Alto Adige, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Ospedale Sacro Cuore Don Calabria

Negrar, Veneto, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04546009

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Azienda Ospedaliera di Alessandria

Alessandria, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Ospedale SS Annunziata

Chieti, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Ospedale Citta' di Castello USL Umbria 1

Città di Castello, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Ospedale San Giuseppe - Azienda USL Toscana Centro

Empoli, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

ASL Lecce - Ospedale "Vito Fazzi"

Lecce, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

ASST Lecco - PO "Alessandro Manzoni"

Lecco, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AULSS 9 Scaligera - Ospedale Mater Salutis

Legnago, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

ASST Ovest Milanese - Ospedale di Legnano

Legnano, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST IRCCS

Meldola, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AOU di Modena

Modena, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Fondazione IRCCS San Gerardo dei Tintori

Monza, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AOU Federico II

Naples, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AOU Maggiore della Carità di Novara

Novara, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

IOV - Istituto Oncologico Veneto - IRCCS

Padova, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

La Maddalena S.p.A.

Palermo, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

ARNAS Ospedale Civico e Benfratelli

Palermo, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AOU Pisana - Stabilimento Santa Chiara

Pisa, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AO Regionale San Carlo

Potenza, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Ospedale Generale Provinciale di Macerata

Province of Macerata, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

GOM "BMM" - Presidio Ospedaliero Morelli

Reggio Calabria, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Azienda USL IRCCS di Reggio Emilia

Reggio Emilia, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

ASL RM 2 Ospedale Pertini

Roma, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AO San Giovanni Addolorata

Roma, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AOU "San Giovanni di Dio e Ruggi d'Aragona"

Salerno, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

IRCCS Ospedale Casa Sollievo della Sofferenza

San Giovanni Rotondo, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AOU Sassari - Ospedale Civile SS. Annunziata

Sassari, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Ospedale San Vincenzo

Taormina, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AOU Città della Salute e della Scienza di Torino - Ospedale Molinette

Torino, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AO Ordine Mauriziano

Torino, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

AULSS n. 2 Marca trevigiana - Ospedale "Cà Foncello"

Treviso, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

ASUFC Udine - Santa Maria della Misericordia

Udine, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

ASST Sette Laghi "Ospedale di Circolo e Fondazione Macchi "

Varese, Italy

· RECRUITING · NCT05945732

DESTINY Breast Respond HER2-(Ultra)Low Europe

Research Site

Catanzaro, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04214288

A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer

Research Site

Catanzaro, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Modena, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT02032823

Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer

Research Site

Modena, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06112379

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Research Site

Modena, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT05374512

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Research Site

Modena, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04305496

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Research Site

Modena, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT04711252

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

Research Site

Modena, Italy

PHASE3 · RECRUITING · NCT06103864

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Research Site

Modena, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT04644068

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Research Site

Modena, Italy

PHASE1, PHASE2 · RECRUITING · NCT05123482

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

Research Site

Modena, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Modena, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Reggio Emilia, Italy

PHASE3 · RECRUITING · NCT06103864

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)

Research Site

Reggio Emilia, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT00099437

Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.

Research Site

Reggio Emilia, Italy

PHASE3 · RECRUITING · NCT06380751

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Research Site

Reggio Emilia, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Genova, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT00099437

Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.

Research Site

Genova, Italy

PHASE3 · RECRUITING · NCT07647328

A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

Research Site

Genova, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Bari, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Grosseto, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Pisa, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Research Site

Turin, Italy

PHASE3 · RECRUITING · NCT05774951

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Ospedale Cottolengo

Torino, TO, Italy

NA · NOT_YET_RECRUITING · NCT07775014

Percutaneous Cryoablation for the Treatment of Breast Cancer

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy

NA · RECRUITING · NCT07776951

Physical Activity and Healthy Aging: Promoting Cardio-metabolic Capacity to Fight Chronic Inflammation and Improve Outcomes in Breast Cancer Patients (PhActHealth Study)

University of Urbino "Carlo Bo"

Urbino, Italy

NA · RECRUITING · NCT07776951

Physical Activity and Healthy Aging: Promoting Cardio-metabolic Capacity to Fight Chronic Inflammation and Improve Outcomes in Breast Cancer Patients (PhActHealth Study)

Asst Papa Giovanni XXIII

Bergamo, Lombardy, Italy

PHASE3 · ACTIVE_NOT_RECRUITING · NCT06065748

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Asst Papa Giovanni XXIII

Bergamo, Lombardy, Italy

PHASE2 · RECRUITING · NCT07405801

A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer

Asst Papa Giovanni XXIII

Bergamo, Lombardy, Italy

PHASE3 · RECRUITING · NCT06790693

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

Asst Papa Giovanni XXIII

Bergamo, Lombardy, Italy

PHASE2, PHASE3 · RECRUITING · NCT07413939

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

Asst Papa Giovanni XXIII

Bergamo, Lombardy, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT05593094

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST S.r.l - PPDS

Parma, Emilia-Romagna, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT05593094

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

Fondazione Policlinico Universitario A Gemelli-Rome

Magnago, Lombardy, Italy

PHASE1, PHASE2 · ACTIVE_NOT_RECRUITING · NCT05593094

A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

Divisione di Sviluppo di Nuovi Farmaci per Terapie Innovative lstituto Europeo di Oncologia

Milan, Milan, Italy

PHASE2 · ACTIVE_NOT_RECRUITING · NCT04579380

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Ospedale di Bolzano

Bolzano, Bolzano, Italy

NA · RECRUITING · NCT07780955

Multimodal Assessment of Cryotherapy for Paclitaxel-Induced Neuropathy

Ospedale di Bressanone

Brixen, Bolzano, Italy

NA · RECRUITING · NCT07780955

Multimodal Assessment of Cryotherapy for Paclitaxel-Induced Neuropathy

Ospedale di Brunico

Bruneck, Bolzano, Italy

NA · RECRUITING · NCT07780955

Multimodal Assessment of Cryotherapy for Paclitaxel-Induced Neuropathy

Ospedale di Merano

Merano, Bolzano, Italy

NA · RECRUITING · NCT07780955

Multimodal Assessment of Cryotherapy for Paclitaxel-Induced Neuropathy

Cliniche Gavazzeni

Bergamo, Italy

PHASE3 · RECRUITING · NCT06382948

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Azienda Ospedaliero-Universitaria (AOU) di Cagliari

Cagliari, Italy

PHASE3 · RECRUITING · NCT06382948

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Aou Careggi

Florence, Italy

PHASE3 · RECRUITING · NCT06382948

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

IRCCS Ospedale Policlinico San Martino

Genova, Italy

PHASE3 · RECRUITING · NCT06382948

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Ospedali Riuniti Livorno

Livorno, Italy

PHASE3 · RECRUITING · NCT06382948

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

Instituto Europeo di Oncologia

Milan, Italy

PHASE3 · RECRUITING · NCT06382948

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

AOU Policilinico Modena

Modena, Italy

PHASE3 · RECRUITING · NCT06382948

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.